Four fire engines and around 25 firefighters were called to a house fire on Pocock Avenue, West Drayton.
The fire damaged half of the ground floor of a semi-detached, two-story house.
Two people left the property prior to crews arriving and were assessed by London Ambulance Service.
Brigade Control Officers were first notified at 2001 with crews from Hayes, Heathrow and Hillingdon fire stations mobilised to the scene. Firefighters were able to bring the incident under control by 2121.
The cause of the fire is under investigation by the Brigade’s Fire Investigation Team.