Four fire engines and around 25 firefighters tackled a fire at a restaurant with dwellings above on Kilburn High Road.
Part of a restaurant on the ground floor was damaged by the fire. Firefighters led 11 people to safety from two flats. There are no reports of any injuries.
One of the Brigade's 32-metre turntable ladders was used at the scene as an observation platform, providing the Incident Commander with an aerial view of the fire.
The Brigade was called at 0640 (25/10). Crews from West Hampstead, Willesden and Paddington fire stations attended the scene. The fire was extinguished by 0757.
The fire is believed to have been accidental and was caused by an electrical fault.