Five fire engines and around 35 firefighters were called to a flat fire on Brook Street in Marylebone.
Part of a kitchen in a two room flat in a 24 storey apartment block was destroyed by fire.
The Brigade's 999 Control officers were called at 1121 and mobilised crews from Soho, Paddington and Shoreditch fire stations. The fire was over by 1202.
The cause of the fire is under investigation.