Six Fire Engines and around 40 Firefighters responded to a commercial fire on Sidcup Road, Eltham.
Firefighters were called to a fire in a ground floor restaurant, which had two floors of flats above. Part of the ground floor was damaged by the fire.
Three people evacuated prior to the Brigade's arrival with no reports of injuries.
Residents in the surrounding area were evacuated and were advised to keep their windows and doors closed due to heavy smoke.
The Brigade’s Control Office was first notified at 1902 with crews mobilised from Eltham, Sidcup, Bromley and surrounding fire stations. Firefighters were able to bring the fire under control by 2124.