Eight fire engines and around 60 firefighters tackled a fire at a pub on Heathfield Road in Keston.
At the height of the fire, part of the first floor, second floor and roof were alight.
One of the Brigade's 32-metre turntable ladders was used at the scene as an observation tower to help fight the fire from above.
Control Officers took the first of six calls at 2233 and mobilised crews from Biggin Hill, Bromley, Orpington and surrounding fire stations to the scene. The fire was under control by 0014.
The cause of the fire is under investigation.