Eight fire engines and around 70 firefighters were called to a fire at a hospital building on Lewisham High Street in Lewisham.
Half of a room on the third floor of a hospital unit of four and five floors was damaged by fire. Fire crews wearing breathing apparatus helped around 15 people evacuate the building.
The Brigade's 999 Control officers received the first of five calls alerting them to the fire at 0222. They mobilised crews from Lewisham, Greenwich, Forest Hill, Lee Green, East Greenwich, Deptford and New Cross fire stations. The fire was under control by 0448.
The cause of the fire is under investigation by the Brigade and the Met police.