Four fire engines and around 25 firefighters responded to a vehicle fire on Aerial Way, Shepherds Bush.
A van, located in a parking structure, was destroyed by the fire. Four people were treated on scene for smoke inhalation, and two of them were removed to hospital by the London Ambulance Service. Around 200 people were evacuated from the building by firefighters.
The Brigade was called about the incident at 1229 and crews from North Kensington, Paddington and Chiswick fire stations were sent to the scene. Firefighters had the incident under control by 1451.
The cause of the fire is not yet known.