Four fire engines and around 25 firefighters attended a fire at a mixed-use building on High Road in Wembley.
Part of the ground floor, which includes a takeaway, was damaged by fire. There were no reports of any injuries.
The Brigade was called at 1154 and Control Officers mobilised crews from Wembley, Northolt, Acton and Ealing fire stations to the scene. The fire was extinguished by 1425.
The cause of the fire is under investigation.