Four fire engines and around 25 firefighters were called to a house fire on Studley Road in Forest Gate.
Half of the ground floor and staircase from the ground floor to the first floor in a terraced house was destroyed by fire.
One woman suffering from smoke inhalation was treated by the London Ambulance Service.
The Brigade's 999 Control officers received a call at 2201 and deployed crews from Stratford, Leytonstone, Plaistow and East Ham fire stations. The fire was under control by 2303.