Four fire engines and around 25 firefighters attended a house fire on Sarsfeld Road in Tooting Bec.
Most of a loft-conversion at a mid-terraced house was damaged by fire. There were no reports of any injuries.
The Brigade received the first of four calls at 1423 and Control Officers mobilised crews from Tooting, Clapham, Battersea and Wandsworth fire stations to the scene. The fire was extinguished by 1535.
The cause of the fire is under investigation.