Four fire engines and around 25 firefighters attended a fire on Yew Tree Walk in Hounslow.
Half of the ground floor and half of the first-floor of a semi-detached house was damaged by fire. There were no reports of any injuries.
The Brigade received the first of five calls at 2016 and Control Officers mobilised crews from Heston, Feltham and Twickenham fire stations to the scene. The fire was extinguished by 2115.
The cause of the fire is under investigation by the Brigade and Metropolitan Police.