Four fire engines and around 25 firefighters tackled a fire at a shop with dwellings above on Prior Street in Greenwich.
Part of a five roomed maisonette on the second and third floors were damaged by the fire. There were no reports of any injuries.
Control Officers took the first of two calls at 1528 and mobilised crews from Greenwich, Lewisham, New Cross and East Greenwich fire stations to the scene. The fire was extinguished by 1617.
The cause of the fire is under investigation.