Four fire engines and around 25 firefighters tackled a fire at a dry cleaners with flats above on Blackhorse Road in Walthamstow.
Most of the ground floor of the property was damaged by fire. Five people left the building before the Brigade arrived uninjured.
The Brigade’s Control Officers took the first of three calls to the fire at 0303 and sent crews from Walthamstow, Leyton and Tottenham fire stations to the scene. The fire was under control by 0500.
The cause of the fire is under investigation.