Six fire engines and around 40 firefighters attended a house fire on Sutton Court Road in Plaistow.
Part of the ground floor, most of the first floor and half of the roof a mid-terraced house was damaged by fire. There were no reports of any injuries.
The Brigade was called at 1236 and Control Officers mobilised crews from Plaistow, East Ham, Barking, Leytonstone and surrounding fire stations to the scene. A 32-metre turntable ladder from Greenwich Fire Station also attended and was used as a water tower to help extinguish the fire from above. The fire was brought under control by 1420.
The cause of the fire is under investigation.