Four fire engines and around 25 firefighters tackled a fire at a block of flats on Fulham High Street.
Half of a four roomed flat was damaged by the fire. One man left the flat before the Brigade arrived. A further 50 people were evacuated from the building before the Brigade arrived. Two people were treated on scene by London Ambulance Service.
The fire is believed to have been accidental and was caused by combustible items left too close to a hob.
A London Fire Brigade spokesperson said: "Fires are more likely to start in the kitchen than any other room in the home.
"You can keep safe by following our simple cooking tips such as never placing anything that can catch fire near the hob. Keep all objects, like tea towels, cloths, plastic bowls and anything flammable well away from the cooker and always check the hob is turned off when you've finished cooking. If you do have to leave the room, turn off the heat and never leave cooking unattended.
"Attempting to extinguish a fire by yourself can lead to injuries or even be fatal and can increase the risk of more severe damage to your property. Leave the room, close the door, shout a warning to others and call 999."
Control Officers took the first of three calls at 2320 and mobilised crews from Fulham, Wandsworth and Hammersmith fire stations to the scene. The incident was over for firefighters at 0201.