Six fire engines and around 40 firefighters tackled a fire at a mid-terraced house on Chelverton Road in Wandsworth.
Most of the ground floor, first floor, second floor and roof were damaged by the fire. One person left the building before the Brigade arrived and was taken to hospital by London Ambulance Service.
One of the Brigade’s 32-metre turntable ladders was used at the scene as a water tower to help fight the fire from above.
Control Officers took the first of 13 calls at 1503 and mobilised crews from Chelsea, Richmond, Hammersmith and surrounding fire stations to the scene. The incident was over for firefighters at 1844.
The cause of the fire has been recorded as undetermined.