Six fire engines and around 40 firefighters tackled a fire at a terraced house on Second Avenue in Dagenham.
A loft extension was destroyed by the fire. There were no reports of any injuries.
Control Officers took the first of seven calls at 2354 and mobilised crews from Dagenham, Barking, Wennington and surrounding fire stations to the scene. The fire was extinguished by 0111.
The cause of the fire is under investigation.