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Four fire engines and around 25 firefighters were called to a house fire on Bramblebury Road in Plumstead.
Part of the ground floor of the property was damaged by the blaze. There were no reports of any injuries.
The Brigade was called at 0859 and the fire was under control by 0942. Fire crews from Plumstead and East Greenwich fire stations were in attendance.
The cause of the fire is under investigation.