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Four fire engines and around 25 firefighters were called to a fire at a house in Vallentin Road in Walthamstow.
Half of the first floor of the property and part of the roof of the property were damaged by fire.
The Brigade's 999 control officers took 14 calls to the fire.
The Brigade was called at 1146 and the fire was under control at 1238. Fire crews from Walthamstow, Woodford and Leytonstone fire stations attended the scene.
The cause of the fire is under investigation.