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Eight fire engines and around 60 firefighters tackled a fire at a waste recycling plant on Chequers Lane in Dagenham.
The fire affected around 120 tonnes of household waste inside a barn. There were no reports of any injuries.
The Brigade was called at 0022 and the fire was under control by 0259. Fire crews from Barking, Dagenham, East Ham, Ilford and Wennington fire stations were at the scene.
The cause of the fire is under investigation.