Twelve fire engines and around 80 firefighters were called to a fire at a block of flats on Wapping High Street.
Part of a flat on the fifth and sixth floors was damaged by fire. Two people left the building before the Brigade arrived. There were no reports of any injuries.
The Brigade was called at 1516 and the fire was under control by 1836. Fire crews from Shadwell, Soho, Dockhead, Shoreditch and surrounding fire stations were at the scene.
The Brigade's fire investigation team believe the fire was accidental and most likely caused by a fault in an inbuilt coffee machine, which will be sampled for further testing.