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Four fire engines and around 25 firefighters were called to a fire at a block of derelict flats on Coralline Walk in Abbey Wood.
Most of a flat on the second floor was damaged by the fire. There were no reports of any injuries.
The Brigade was called at 2121 and the fire was under control by 2214. Fire crews from Plumstead, Erith and Bexley fire stations were at the scene.