Twelve fire engines and around 80 firefighters, as well other specialist vehicles, were called to a burst water main at the junction of Queens Drive and Princess Crescent in Finsbury Park.
The road was flooded to a depth of around one metre. Around 250 properties were affected. Firefighters rescued one man from the basement of a building and crews led other residents to safety.
Station Manager Jonathan Parker, who was at the scene, said: "We worked closely with Thames Water who had a specialist engineer on site. Crews visited affected properties and led residents to safety where necessary.
"They also worked hard to pump water away from the area and prevent flooding from spreading to other properties."
The Brigade has a range of equipment which can be used to help rescue people trapped by flood water, pump water away and protect properties.
Queens Drive and Brownswood Road were closed to traffic.
The Brigade's 999 Control Officers took 49 calls to the flooding.
The Brigade was called at 0747 and the incident was over for firefighters by 1819. Fire crews from Holloway, Stoke Newington, Islington, Kentish Town and Tottenham fire stations attended the scene.