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Three fire engines and three fire rescue units were called to a ceiling collapse at a theatre in Piccadilly.
A section of plaster ceiling fell onto the third floor seating area in the six storey building.
Approximately 1,100 people evacuated before the Brigade arrived.
Three men and two women were treated on scene by London Ambulance Service for cuts and injuries caused by falling debris.
The Brigade was called at 2003 and the incident was over for us by 2105.