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Four fire engines, two fire rescue units and around 30 firefighters were called to a ceiling collapse at a hotel on Piccadilly, W1J.
A plaster ceiling in the ground floor lobby collapsed due to a water leak.
Approximately 500 people were evacuated from the hotel as a precaution. There were no reports of any injuries.
Firefighters carried out a systematic search of all floors of the hotel.
The Brigade was called at 1636 and the incident was over for firefighters at 1943. Fire crews from Chelsea, Soho, Kensington, Lambeth attended the scene.