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Four fire engines and around 25 firefighters were called to a fire at a house in Holmwood Road in Ilford.
A car parked on a driveway was destroyed by fire and a small section of a front porch was damaged by fire.
Firefighters assisted one man and two women from a flat roof. They were assessed at the scene by London Ambulance Service crews.
The Brigade was called at 0412 and the fire was under control at 0443. Fire crews from Ilford and Barking fire stations attended the scene.
The cause of the fire is under investigation.