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Four fire engines and around 25 firefighters were called to a fire in the basement of a church on Laxton Place in Euston.
A boiler room in the basement was destroyed by fire. There were no reports of any injuries.
The Brigade was called at 2307 and the fire was under control at 0032. Fire crews from Soho, Paddington, and Euston fire stations attended the scene.
The cause of the fire is under investigation.