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Four fire engines and around 25 firefighters were called to a fire at a flat on Fernhead Road in Maida Vale.
Most of a first floor flat above a restaurant was damaged by the fire. There were no reports of any injuries.
The Brigade was called at 0700 and the fire was under control by 0818. Fire crews from North Kensington and Paddington fire stations attended the scene.
The cause of the fire is under investigation.