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Four fire engines and around 25 firefighters were called to a fire at a maisonette on Southend Crescent in Eltham.
A maisonette on the second and third floors was destroyed by the fire. Two women, a man and a baby left the property before the arrival of the brigade. They were all treated at the scene for smoke inhalation by London Ambulance Service crews. A further 15 people also left the building before the Brigade arrived.
The Brigade's 999 Control Operators took 12 calls to the fire.
The Brigade was called at 2135 and the fire was under control by 2135. Fire crews from Lee Green, Forest Hill, Plumstead and Eltham fire stations attended the scene.
The Brigade’s fire investigation team believe the cause of the fire was due to an electrical fault in a tumble dryer.