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Eight fire engines and around 60 firefighters were called to a fire at a restaurant with flats above on Endell Street in Soho.
The restaurant's ducting – the ventilation system – from the basement to the roof level on the third floor was alight and crews worked hard to extinguish the fire. No injuries are reported.
The fire is believed to be caused by deep fat frying.
A London Fire Brigade spokesperson added: “Restaurant and take-away owners should always take care to make sure their extraction systems are kept clean as a build up of fat and grease within the filters can lead to a fire.”
The Brigade was called at 1437 and the fire was under control by 1744. Fire crews from Soho, Euston, Dowgate, Lambeth, Islington, Whitechapel and Shoreditch fire stations were at the scene.