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Three fire engines and a fire rescue unit were called to a boat which taking on water and stuck under a bridge in Commerce Road, Brentford.
Firefighters rescued two men, who were stuck on the boat, by ladder. There were no reports of any injuries.
The Brigade was called at 1747 and the incident was over for firefighters at 1836. Fire crews from Heston, Acton and Wembley fire stations attended the scene.