Eight fire engines and 58 firefighters and officers were called to a flat fire in Wellington Way, Mile End.
Most of a three-roomed flat on the 12th floor was damaged by the fire and part of the balcony of the 13th floor was also damaged. Around 44 people left the building before the Brigade arrived and a further two people were led to safety by firefighters. There were no reports of any injuries.
The Brigade’s 999 Control Officers took more than 90 calls to the fire.
The Brigade was called at 1228 and the fire was under control at 1351. Fire crews from Bethnal Green, Shadwell, Stratford, Whitechapel and surrounding fire stations are at the scene.
The cause of the fire is under investigation.