Four fire engines and 21 firefighters and officers were called to a fire at a house in Amberley Road, Enfield.
Half of the ground floor of the mid-terraced house was damaged by fire.
Fire crews wearing breathing apparatus rescued a woman from the ground floor of the property, but sadly she was pronounced dead at the scene.
The Brigade was called at 2134 and the fire was under control at 2236. Fire crews from Edmonton, Southgate and Tottenham fire stations attended the scene.
The cause of the fire is under investigation.