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Two people were led to safety by firefighters after a fire at a house in Lindley Street in Whitechapel.
Part of the ground floor of the property was damaged by fire.
A woman and a child were led to safety via an internal staircase by breathing apparatus crews and were treated for shock at the scene by London Ambulance Service crews.
The Brigade was called at 0215 and the fire was under control at 0247. Fire crews from Shadwell and Bethnal Green fire stations attended the scene.
The cause of the fire is under investigation by the Metropolitan Police Service.