Four fire engines and 21 firefighters and officers were called to a fire at a mid terraced house in Askew Road, Shepherds Bush.
Part of the lower ground floor, which is converted into flats, was damaged by fire.
Two people left the property before the arrival of the Brigade and a further five people were evacuated by firefighters.
The Brigade was called at 0414 and the fire was under control at 0518. Fire crews from Acton, Hammersmith and Chiswick fire stations attended the scene.
The cause of the fire is under investigation.