Eight fire engines and 58 firefighters and officers are tackling a fire at a restaurant with flats above on Woodgrange Avenue in Ealing.
Firefighters rescued two men via a ladder. They were both uninjured. Part of the ground floor, first floor and roof was damaged by the blaze.
The Brigade was called at 0510 and the fire was under control at 0754. Fire crews from Acton, Ealing, Chiswick, Park Royal, Hammersmith and Wembley fire stations were at the scene. The cause of the fire is under investigation.